I run Facebook ads all day at my job and you're definitely going to have to pay much more for ads in U.S. (over Canada or anywhere else). In addition, starting your ads at a lower CPC will get you a lower quality score for your ad -- so even if you get served initially, the life-span of your ad getting served on Facebook will be much less. You will then have to reupload and start spending at a higher CPC much quicker. Of course if you're a small business, starting out at a much higher CPC (>$1) and running a lot of initial volume might not be feasible for most people. You need to start out with greater than .100% CTR if you want to have the ad sustain for a long period of time. Running celebrity ads for a short period of time will work, but you could be looking at C&D at some point if you're running a huge amount of volume.

Edit: At the end of the day CPC and CTR are useless if you can't drive enough volume from the ads based on your targeting.

Edit 2: Targeting 30+ women will get you a higher landing page conversion and CTR (obviously depends on the vertical, but in general).